This Dr Pepper Barbecue Sauce has been a longtime family favorite—rich, sweet, and smoky. Reducing a portion of the Dr Pepper concentrates its distinctive flavor, while gently warming the spices brings out their aroma. Brown sugar, honey, and molasses give the sauce a rounded sweetness, balanced by apple cider vinegar and savory seasoning. Brush it onto meat near the end of cooking or serve it warm on the side.
Ingredients
- 1 bottle, 20 fl oz (591 ml), Dr Pepper, divided
- 2 cups (480 g) ketchup, divided
- About ¾ cup (150 g) brown sugar
- 2 tbsp (40 g) molasses
- ¼ cup (84 g) honey
- ¼ cup (60 ml) apple cider vinegar
- 2 tsp liquid aminos
- 1 tsp fish sauce
- 1 tsp chipotle chili powder
- ½ tsp garlic powder
- ½ tsp table salt
- ¼ tsp ginger powder
- ¼ tsp galangal powder, or substitute an additional ¼ tsp ginger
- ¼–½ tsp black pepper
Directions
Reduce The Dr Pepper
Pour 1 cup (240 ml) of the Dr Pepper into a saucepan and simmer over medium heat until reduced to a thick, syrupy consistency, about 10–15 minutes. Set aside.
Bloom The Spices
In a large saucepan, warm 2–3 tbsp (30–45 g) of the measured ketchup over medium heat.
Add the chipotle chili powder and garlic powder, stirring constantly for 30–60 seconds until fragrant.
Build The Sauce
Add the remaining Dr Pepper, reduced Dr Pepper syrup, remaining ketchup, brown sugar, molasses, honey, apple cider vinegar, liquid aminos, fish sauce, salt, ginger, galangal, and black pepper.
Stir well to combine.
Simmer Until Thickened
Bring the sauce to a gentle boil, then reduce to a simmer.
Cook uncovered, stirring occasionally, until thickened to your desired consistency, about 20–30 minutes.
Taste And Adjust
Taste and adjust with additional vinegar for brightness or a pinch of salt if needed.
Yield: About 4 cups (950 ml).
Notes
Preparation
- Reducing part of the Dr Pepper concentrates its flavor and enhances the signature character of the sauce.
- Blooming the spices helps develop deeper, more integrated flavor compared to adding them directly to the liquid.
- The combination of brown sugar and molasses provides a more balanced, less candy-like sweetness.
Variations
- Root Beer or Cola: Root beer or cola may be substituted for Dr Pepper for a slightly different flavor profile.
- Tangier Sauce: For a slightly tangier sauce, increase the apple cider vinegar by 1–2 tsp.
Serving Suggestions
- Perfect for pulled pork, ribs, grilled chicken, or burgers.
- Brush onto meats during the final stage of cooking or serve warm on the side.
Make-Ahead & Storage
- Refrigerate in a sealed container for up to 1 week.
- Reheat gently before serving if desired.
- The flavor deepens after a day in the refrigerator.





